Ex vivo p19 production from cultured rabbit lymphocytes. Rabbit lymphocytes were isolated from PBMC and cultured for 24 hours. p19 MA, a measure of virus expression, was measured on a HTLV-1 ELISA. (A) Rabbits treated with 10 mg/kg and 20 mg/kg CsA displayed significant increases in ex vivo p19 production compared with control rabbits at 1 and 2 weeks after infection. (B) Rabbits receiving 20 mg/kg CsA after infection had their ex vivo p19 production abolished after the start of CsA treatment.