Only mature Plasmodium falciparum–infected erthryocytes are able to bind to platelet-decorated VWF strings on endothelial cells stimulated with histamine. (A) Ethidium bromide–labeled parasites (Δ) are the only red blood cell species binding to the platelet–decorated VWF strings ↑. Flow direction is from left to right. (B) Trophozoite (Troph) IE binding to strings (n = 11) was significantly blocked by a CD36 monoclonal antibody (n = 4). Similarly, binding was not observed in the presence of uninfected red blood cells (n = 4) or with ring-stage IE (n = 3). Bar represents 20 μm. **P < .005.