Chromosomal alterations associated with an unfavorable prognosis and their putative target genes. (A) Loss of 9p. (B) Double loss of 9p21.3. (C) Loss of 1q32. (D) Double loss of 1p32.3/33. (E) Amplification of 12q14. (F) Double loss of 2q13. Kaplan-Meier curves visualize survival differences between MCL patients with and without the respective CNA. (Right panels) Genes within the MCR that had the greatest difference in fold change in cases with the alteration compared with the cases without the alteration. In the gene expression panels, only genes within the core region of the respective MCR are shown. Genes with a P value more than .05 are shown in gray.