Kaplan-Meier plots showing influence of IDH1 mutations according to NPM1 mutational status. (A) Inferior EFS of IDH1-mutated AML (in red) compared with IDH1 wild-type cases (black) only in cases without NPM1 mutation (right side), but not in the NPM1-mutated cases (left side). (B) CRR is shown for the NPM1wt cohort.