Adjusted mean differences between CML patients and their respective control groups by sex. (A) Physical health and (B) mental health. A score below 0 line means worse outcomes for CML patients. Note that connecting lines among SF-36 outcomes are plotted only for descriptive purposes. *Statistically significant after Bonferroni adjustment (adjusted α = 0.05/8= 0.00625). Statistical significance refers to the group specific adjusted mean differences of SF-36 scores between CML patients and matched control subjects. †Mean difference between CML patients by sex and the respective matched control subjects adjusted for age, education, geographical area, and marital status. A negative sign indicates worse outcomes for CML patients. ‡Exceeds minimally important difference (ie, 8 points for the SF-36 scales and 2 points for the PCS and MCS scores). §Statistically significant (α = 0.05).