Ang-2 augments DTH and peritonitis in transgenic mice. After induction of DTH, leukocyte infiltration was measured in DNFB-treated ears (A). Severely increased ear swelling was evident in Ang-2 DT as shown by H&E staining (A). Quantification revealed significantly increased ear diameters in Ang-2 DT compared with WT mice (B). ***P < .005, compared with untreated ears. #P < .001, compared with treated WT ears. In a model of thioglycollate-induced peritonitis, peritoneal neutrophils were identified according to the expression of Ly-6G and Ly-6C and counted by FACS (C). After thioglycollate challenge, transgenic animals showed significantly increased numbers of myeloid cells in the peritoneal cavity (C-D). Among those, neutrophils (Ly-6G⁺/Ly-6C⁺) and monocytes (Ly-6G⁻/Ly-6C⁺) were prominent (C-D). Data are mean ± SEM; n = 4. *P < .05. ***P < .005.