ETV6-RUNX1 expression in mouse preleukemic models is associated with increased levels of EPOR. (A) Quantitative PCR detection of EPOR in a murine BaF3 cell line (1/27) induced to express ETV6-RUNX1 (1/27 + MIF) or a mock-induced control (clone 1 + MIF; n = 4; P = .007). (B) Quantitative PCR detection of EPOR in a Sca1⁺ Kit⁺ population isolated from a transgenic E μ-ETV6-RUNX1 mouse model (n = 6). (C) Detection of functional ligand-binding EPOR in the E μ-ETV6-RUNX1 mouse model by FACS (n = 22; P = .033).