Platelet recovery is attenuated in Cib1−/− mice after immune-induced thrombocytopenia. (A) Time course of platelet recovery from WT and Cib1−/− mice, every 24 hours for 7 days after injection of an anti–mouse CD41 antibody. *P < .05 vs WT (n = 8). (B) Time course of platelet recovery after experimentally induced thrombocytopenia expressed as a percentage of original platelet count. (C) Quantification of DNA content from WT and Cib1−/− megakaryocytes 72 hours after injection of a mouse anti-CD41 antibody.