Correlation of Bcl-2 protein expression, severity of cGVHD, and telomerase activity. Bcl-2 expression of Tcon and Treg was measured by flow cytometry. Relative Bcl-2 expression was calculated by dividing the median MFI of Bcl-2 by the median MFI of isotype matched IgG. (A) Bcl-2 expression of Tcon and Treg in healthy subjects (HS) and patients after HSCT. P values indicate comparisons for each category. (B) Bcl-2 expression of Tcon in healthy subjects and patient subsets based on severity of cGVHD. N.S. indicates not significant. (C) Bcl-2 expression of Treg in healthy subjects and patient subsets based on severity of cGVHD. (B-C) P values indicate comparisons among patient subsets. (D-E) Relationship between telomerase activity and each Bcl-2 expression in Tcon (D) and Treg (E). Correlation was calculated using Spearman rank test.