Grp78 heterozygosity suppresses PTEN null-mediated blast cell expansion and prolongs survival. (A) Representative results of leukemic blast cell identification. P1 population in green represents the neutrophil region. P2 population in red represents leukemic blast cell region. (B) Quantitation of the leukemic blast cell percentages of WT (n = 7), cP^f/f (n = 7), and cP^f/f78^f/+ (n = 10) shown in panel A. Data are mean ± SE. **P < .01 (Student t test). (C) Kaplan-Meier survival curve of WT (n = 10), Pten null (cP^f/f, n = 14), Pten null, Grp78 heterozygous mice (cP^f/f78^f/+, n = 21), and Grp78 heterozygous mice (c78^f/+, n = 5).