Cartoon showing possible repressor complexes formed through mutually exclusive recruitment of TRIM28, HDAC3, or the NuRD or CoREST complex by the DRED heterodimer of NR2C1 (formerly TR2) and NR2C2 (formerly TR4). The figure has been adapted with permission from Figure 8 in the article by Cui et al.5 Professional illustration by Debra T. Dartez.