Marked reduction of peripheral lymphadenopathy was observed after treatment with autologous 19-28z+ T cells. Representative computed tomography scan images of patient CLL-5 before treatment and from 4 weeks and 14 weeks after treatment show mild increase in axillary (top) and pelvic lymphadenopathy (bottom) at 4 weeks but regression of lymphadenopathy at 14 weeks after therapy with modified T cells.