IGSF4 gene expression in pediatric AML as determined by RT-qPCR. Graph showing the expression of IGSF4 on mRNA level measured with RT-qPCR. Bars represent the median expression in each group. Significant differences are observed between patients with a t(9;11) (n = 24) and patients with another MLL-rearrangement (MLL other, n = 33; (6.4 vs 0.9, P = .008) or AML patients without a MLL rearrangement (AML other, n = 38; 6.4 vs 0.02, P < .001).