Expression and regulation of proteomic targets in monocytes from patients with APS. Ex vivo monocytes from 3 patients with VT and 3 age-matched HC were left untreated or stimulated with 100 ng/mL LPS for 6 hours or overnight and mRNA levels were measured by qPCR (A-D). Data points represent the mean of duplicates and standard errors are displayed. Statistically significant difference (*P < .05, **P < .005, ***P < .001) was determined by paired Student t test. LPS, lipopolysaccharide.