Distribution of histone modifications, and active, intermediate, and poised enhancers in human primary Tfh and Teff cell chromatin. The human genome was portioned into 7 bins relative to RefSeq genes. The percentage of the human genome represented by each bin was color coded, and the distribution of peaks of each histone modification and enhancer class, active, intermediate, and poised, in each bin graphed on the color-coded bar. (A) Tfh cells. (B) Teff cells. (C) K562 cells are included as a nonlymphocyte, hematopoietic cell type for comparison. TES, transcriptional end site.