Hypothetical model for the spectrum from CLL, B-PLL, and MCL. CLL is different from MCL and B-PLL. Some B-PLL cases, probably all t(11;14)-negative, have some similarities with CLL and may have a relatively good prognosis (CLL-like B-PLL). Another subgroup of B-PLL is indistinguishable from leukemic MCL patients (leukemic MCL-like B-PLL); this subgroup contains both t(11;14)-positive and t(11;14)-negative patients. A third B-PLL subgroup is comparable to but distinguishable from nodal MCL (nodal MCL-like B-PLL).