Representative staining of bone marrow aspirates collected from a patient at baseline and after 1 cycle of treatment with 45 mg/m²selinexor + 20 mg dexamethasone, twice weekly. The patient achieved a best response of PR while on study. Staining shows increased apoptosis (Apoptag) and nuclear accumulation of known TSP cargoes of XPO1 (p53, survivin, Rb, and Smad4).