American Society of Hematology

Figure 4.

$Figure 4. Dosimetry of 90Y-DOTA–biotin using CD38-bispecific PRIT. Dosimetry, absorbed radiation dose per unit administered activity (Gy/mCi), was calculated for tumor and normal organs during the first 120 hours after radioactivity injections (tissues per Figure 3B). Dosimetry includes organ self-dose absorbed fraction plus β-particle cross-organ absorbed fraction.45 Absorbed radiation dose to tumor was 44 Gy/mCi, in contrast to 6, 3, and 3 Gy/mCi for liver, lung, and kidney, respectively.$

Dosimetry of ⁹⁰Y-DOTA–biotin using CD38-bispecific PRIT. Dosimetry, absorbed radiation dose per unit administered activity (Gy/mCi), was calculated for tumor and normal organs during the first 120 hours after radioactivity injections (tissues per Figure 3B). Dosimetry includes organ self-dose absorbed fraction plus β-particle cross-organ absorbed fraction.⁴⁵ Absorbed radiation dose to tumor was 44 Gy/mCi, in contrast to 6, 3, and 3 Gy/mCi for liver, lung, and kidney, respectively.

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