Chimerism kinetics. Peripheral blood chimerism posttransplant. (A) PBMC chimerism results at 3, 6, and 12 months (n = 20, 17, and 19, respectively): full donor chimerism (≥97% donor DNA) was achieved in PBMC fraction in 71% at 3 months, 83% at 6 months, and 85% at 12 months. (B) T-cell chimerism results: full donor chimerism was achieved in the T-cell fraction in 30% at 3 months, 41% at 6 months, and 52% at 12 months. (C) B-cell chimerism: full donor chimerism was achieved in the B-cell fraction in 65% at 3 months, 82% at 6 months, and 69% at 12 months. (D) Chimerism in the granulocyte fraction. Full donor chimerism was seen in 83% patients at 3 months, 67% at 6 months, and 67% at 12 months.