IPA core analysis–based associated networks. (A) normal EVs vs normal whole cells: Cell-To-Cell Signaling and Interaction, Nervous System Development and Function, Neurological Disease (score 38) and (B) ABC EVs vs ABC whole cell lines: cancer, hematological disease, immunological disease (score 30). Red represents positive enrichment, and green represents negative enrichment in the EVs compared with the respective whole cell. Links of validated genes and other genes or molecules are represented with a continuous (direct interaction) or discontinuous line (indirect interaction).