Landmark analysis of survival after 6 months and 1 year post-HCT according to CD4⁺cell counts and ROC curves of predictive value of CD4⁺counts at 6 months and 1 year for long-term T-cell reconstitution. Kaplan-Meier plots estimating survival for all patients who were alive at 6 months (A) or at 1 year (B) and did not receive second treatment according to CD4⁺ cell count, with log-rank test applied to evaluate the association. Estimates and 95% CIs were provided at each time point. ROC curve showing the predictive value of CD4⁺ cell counts at 6 months (C) or at 1 year (D) posttransplant for long-term T-cell reconstitution at 2-5 years (red) or 6-10 years (blue). Area under the ROC curve is 0.807 for 2-5 year outcome and 0.678 for 6-10 year outcome (C) and 0.890 for 2-5 year outcome and 0.755 for 6-10 year outcome (D).