Figure 2.
Recurring SEs are associated with TF genes in MM cells and normal controls. (A) SEs identified by ROSE in MM, memB, and PB cells. Selected TFs included in panel C are indicated. (B) SE-associated genes are expressed higher than genes associated with TEs. Box and whiskers plots display FPKM for SE- or TE-associated genes. ***P ≤ .001. (C) Heat map of SE-associated TF genes identified by ROSE in at least 6 MM samples. The blue color indicates the presence of an SE that is associated with the indicated TF gene. The 4 identified clusters (I to IV) are indicated.