Thromboxane B2 release. Data are mean ± SEM (pg/ml) for all patients at baseline (BL), after pioglitazone alone (Pio), after aspirin alone (ASA) and after both aspirin and pioglitazone (A+P). Release with Pio alone was significantly less than at BL (p =.0004), and release with A + P was significantly less than with ASA alone (p <.0001).