Patterns of LOH on chromosome 16. The first bar in each panel indicates LOH status with retention of heterozygosity (yellow) and LOH (blue). The second bar in each panel indicates copy number with dark pink indicating normal diploid copy number and pale pink indicating deletion. The blue line indicates copy number relative to the red line (copy number of 2) with a line to the left indicating deletion. The chromosome graphics are representations of each inherited chromosome (purple and green). (A) The normal diploid situation. (B) Acquired UPD of the entire chromosome 16 in 2 cases. (C) Acquired UPD of 16q in 2 cases. (D) Deletion of the entire chromosome 16 in 2 cases. (E) Deletion of 16q in 10 cases. (F) Interstitial deletion of varying regions of 16q in 7 cases.