CYP3As and MDR1 mRNA quantification in PTCL tumors. (A) CYP3A mRNA content in PTCL tumors. CYP3A4 mRNA expression was quantified by real-time RT-PCR in 45 PTCL tumors: 23 PTCLu's, 15 AITLs, and 7 NKs. Results are expressed relative to CYP3A4 expression in control tissue (reactive lymph nodes). Error bars represent SD of 3 independent experiments. (B) Correlation between CYP3As and MDR1 expression in PTCL tumors. The mRNA expression of CYP3A4, CYP3A5, CYP3A7, CYP3A43, and MDR1 in 45 PTCLs was compared by correlation analysis. The results obtained for CYP3A4 are shown with the correlation coefficients and P values.