E10.5 wild-type and EKLF^−/−KLF2^−/− whole-mount embryos. Panels A and B are wild-type (WT), and panels C and D are EKLF^−/−KLF2^−/− E10.5 embryos. In panels A and C, embryos are surrounded by yolk sacs. Panels B and D are the same embryos, respectively, with yolk sac teased away, but vitelline and umbilical vessels still intact. Photographs were taken at 16× magnification. See “Analysis of EKLF^−/−KLF2^−/− embryos” for more image information.