Expression of cell activation- and apoptosis- related molecules in CD38⁺ and CD38⁻ cell subsets within patients with CLL. PBMCs from 50 patients with CLL were analyzed for expression of CD27, CD62L, or CD69 by CD5⁺, CD19⁺, and CD38⁺ cells. (A-C) Significant differences in expression of CD27, CD62L, and CD69, respectively, within CD38⁺ and CD38⁻ subsets of the clone (CD27 and CD62L, P < .001; CD69, P < .01). (D) Means (± SE) for percentage of Bcl-2⁺ cells (left) and means (± SE) for MFI of Bcl-2 expression (right).