Human hematopoietic engraftment in NOD/SCID mice by CD34⁺ACE⁺ fetal liver cells. Representative examples displaying analysis of BM from NOD/SCID recipients of CD34⁺ACE⁺ cells sorted from a 14-week human fetal liver. Analyses were performed 4 months after transplantations. (A) Percentage of human CD45⁺ cells in individual animals that received a transplantation of 1 × 10³, 2 × 10³, 5 × 10³, and 10 × 10³ CD34⁺ACE⁺ cells. Horizontal lines represent the average percentage of human CD45⁺ cells in each group. (B) Representative example of multilineage human hematopoietic engraftment in an animal that received a transplantation of 1 × 10³ cells. (C) Four mice that received a transplantation of 1 × 10³, 2 × 10³, 5 × 10³, and 10 × 10³ CD34⁺ACE⁺ cells. The percentages indicate the significant proportion of human CD45⁺ cells within the BM represented by CD34-expressing cells.