Hydrogen peroxide production by neutrophil granulocytes stimulated with IVIg-F(ab′)2. (A) Gray curve indicates TNFα + PBS; black curve, TNFα + IVIg (batch B1). (B) Gray curve indicates TNFα + PBS; black curve, TNFα + IVIg-F(ab′)2 (batch A4). IVIg concentration 2.5 mg/mL, IVIg(Fab′)2 concentration 1.6 mg/mL, incubation time 80 minutes. Cells were prestimulated with TNFα (1 ng/mL) for 15 minutes.