Subpopulation of naive and memory CD4 and CD8 T cells in lymph nodes of patients with chronic HIV-1 and patients without HIV-1. Cells were phenotyped by flow cytometry at day 1 after surgery. Presented are the mean numbers of living T cells expressing CD4 (A-B) or CD8 (C-D) in lymph nodes from infected (A and C) or uninfected (B and D) individuals. The results represent means of the data obtained with sets of 3 tissue blocks derived from 8 donors with HIV-1 and 5 patients without HIV-1. ▪ indicates the mean for central memory T cells; ⊡, the mean for naive T cells; and □, effector T cells. *P < .05 for the difference between chronic HIV-1–infected and uninfected control tissue as evaluated by nonparametric Mann-Whitney test. (A) CD4 T lymphocytes subpopulation in chronic HIV-1–infected lymph nodes. (B) CD8 T lymphocyte subpopulation in chronic HIV-1–infected lymph nodes. (C) CD4 T lymphocyte subpopulation in uninfected control lymph nodes. (D) CD8 T lymphocyte subpopulation in uninfected control lymph nodes.