AChE activity decreases in the myasthenic thymus. (Ai) AChE hydrolytic activities in thymic homogenates from MG patients compared with newborns (NB) and nonmyasthenic adults. (Aii) Cytoplasmic AChE activity decreases in MG thymus compared with NB thymus (P ≤ .04). (Aiii) Membrane-associated AChE activity decreases in the thymus of MG patients compared with newborns (P ≤ .002) and healthy adults (P ≤ .04). (Aiv) Tailed AChE activity decreases in the thymus of MG patients compared with newborns (P ≤ .01) and healthy adults (P ≤ .008). Error bars show standard error of the mean (SEM). *P < .05. (B) Cumulative analysis highlighting differences in the changes described. Note conspicuous decreases in activity of adult soluble AChE and MG-associated membrane-adhered enzyme.