Mice that received transplants of MBECs demonstrate accelerated BM cellular recovery following total body irradiation. C57Bl6 mice were irradiated with 700 cGy total body irradiation and then observed without treatment or given transplants of 5 × 105 MBECs daily for 5 days. BM cells were collected from bilateral femurs from mice in each condition at day 0 and every 5 days through day +30, and mean viable mononuclear cell (MNC) counts were performed. Standard errors for each mean are shown as error bars. Mice that received transplants of MBECs demonstrated significantly increased numbers of viable MNCs at day +15, +25, and +30 compared with irradiated control mice. The * indicates a significant difference at each time point; P = .004, P = .001, P = .019, respectively.
