Proposed scheme of the redox transitions of Prx2. Schematic representation of the proposed redox behavior of Prx2 when erythrocytes (A) and Jurkat cells (B) are treated with high concentrations of H2O2 (∼ 100-200 μM). SpH indicates peroxidatic cysteine, Cys50; SrH, resolving cysteine, Cys171.