Development of anemia induced by the 34-3C IgM, IgA, and IgG2a variants in BALB/c mice. Mice were injected intraperitoneally with 10 (◆), 25 (•), or 100 (○) μg of 34-3C variants on day 0. Results are expressed as mean Ht values (±SD) of 3 mice. Decreases in Ht values 2 and 4 days after injection of 34-3C IgM, IgA, or IgG2a, as compared with Ht values at day 0, were significant for all 3 doses tested (P < 0.05).