Cell-cycle analysis. (A) MOLM13 or (B) PALL2 cells (5 × 105/mL) were plated in 24-well plates and cultured with various concentrations of AZD1152-HQPA (1-10 nM). After 24 or 48 hours, cells were harvested and cell-cycle distribution was analyzed by FACScan. Results represent 1 of the experiments performed 3 times in duplicate plate. Arrows indicate population with 2N, 4N, and 8N DNA content.