Evaluation of hematopoietic phenotype of Vegfhi/+ and wt mice. Spleens from 8- to 10-week-old Vegfhi/+ and age-matched wt controls (n ≥ 3 mice/group) were harvested and prepared for enumeration of B, T, and NK cells by flow cytometry as described in “Materials and methods.” (A) Percentage of B, T, and NK cells from spleens of Vegfhi/+ and wt mice. **P < .05 when compared with wt control. (B) A representative dot plot of B220+ and CD3+ splenocytes from Vegfhi/+ and wt mice that were evaluated by flow cytometry. (C) A representative dot plot of B220+ and CD19+ splenocytes from Vegfhi/+ and wt control mice.