NK cell activity analysis in Vegfhi/+ or BALB/cJ mice administered VEGF-A. NK cell activity analysis was performed for either Vegfhi/+ (A,C) or BALB/cJ wt (B) mice administered with 500 ng rmVEGF-A164. (C) Spleen cells were cocultured with either Yac-1 target cells (A,B) or CB3 erythroleukemia cell line. The effector-target ratios are shown on the x-axis. The PSL values are shown on the y-axis and calculated according to “Materials and methods.”