Delineation of MDRs. Delineation of MDRs is shown for chromosomes (A) 13q and (B) 4q. The top panels show the microsatellite markers analyzed and their respective chromosomal locations. Vertical lines on the right denote the MDRs defined in each chromosomal region, and candidate genes selected for further mRNA expression analysis are listed beside the MDRs. Filled circles denote allelic imbalance (AI); unfilled circles, retention (R); and dash, noninformative at each specific loci examined. The electropherograms of representative cases for defining the MDRs are shown in the bottom panels.