Diagrammatic representation of BMP and Jak/Stat signaling pathways. Chordin (Chd), together with other BMP antagonists such as twisted gastrulation, blocks the binding of BMP to its receptor. Therefore, knock-down of Chd with MO enhances BMP signaling.⁸  Potential cross-talk between BMP and Jak/Stat signaling pathways are shown by the dotted lines.