Hierarchic cluster analysis of DNA methylation data. BL indicates Burkitt lymphoma; NHL, non-Hodgkin lymphoma; ABC, activated B-cell like; GCB, germinal center B-cell like; mBL, molecular Burkitt lymphoma; and DLBCL, diffuse large B-cell lymphoma. The bar plot (complexity) below the upper dendrogram points to the number of chromosomal imbalances in each case detected by array CGH as a measure of chromosomal complexity. This analysis shows that DNA methylation patterns are not strictly associated with morphologic, genetic, or transcriptional features.