CD45 mAb infusion induces a transient increase of IL-15 and EBV-DNA. Plasma (A) IL-15 and (B) IL-7 levels were determined with ELISAs. IL-15 levels increased significantly, whereas IL-7 levels remained unchanged. (C) EBV-DNA load increased transiently in 4 patients. (D) Patients with the lowest EBV-specific T-cell precursor frequency had the highest increase in EBV-DNA load.