Multilineage reconstitution of transduced cells in oc/oc+tcirg1 mice and reversal of peripheral blood B-cell deficiency in oc/oc+tcirg1 mice. (A) The peripheral blood of an 18-week-old oc/oc+tcirg1 mice was analyzed for expression of GFP and lineage markers. Percentage positive cells as indicated in the graph. (B) The percentage of B220-positive cells in the peripheral blood of oc/oc, oc/oc+tcirg1, and WT mice was analyzed at the time points indicated. The mean value and SD is shown (n = 4-6 mice per group).