Serology of New Zealand black × New Zealand white mice after transplantation. Serum was screened by enzyme-linked immunosorbent assay for titers of circulating immune complexes (CIC), and autoantibodies to dsDNA, nuclear antigen, and histone. Serum was collected before death or at the conclusion of the study. The levels of CIC and all autoantibodies analyzed was significantly lower in the mice that received allogeneic hematopoietic stem cells (red) than in mice that received syngeneic hematopoietic stem cells (blue) or whole bone marrow (green) and the age-matched control mice (gray) (P ≤ .001). Horizontal lines represent mean of each group. Serum from donor strain mice, DBF, was used to establish baseline levels of autoantibodies. Data were combined from 3 experiments.