Figure 3
Figure 3. Impact of early antiretroviral treatment on plasma viral load, CD4+ T-cell counts, and pDC dynamics in blood and lymph nodes. Changes of each parameter in 6 individual macaques infected with 50 AID50 of SIV (solid black lines) that received ART from 4 hours to 28 days after virus inoculation (50 AID50 + ART group). (A) Plasma viral loads. (B) Blood CD4+ T-cell counts. (C) Absolute pDCs counts in the blood. (D) Absolute numbers of pDCs in peripheral lymph nodes. Dotted lines in A: median plasma viral load of the 50 AID50 group (gray) and of the 5000 AID50 group (black).

Impact of early antiretroviral treatment on plasma viral load, CD4+ T-cell counts, and pDC dynamics in blood and lymph nodes. Changes of each parameter in 6 individual macaques infected with 50 AID50 of SIV (solid black lines) that received ART from 4 hours to 28 days after virus inoculation (50 AID50 + ART group). (A) Plasma viral loads. (B) Blood CD4+ T-cell counts. (C) Absolute pDCs counts in the blood. (D) Absolute numbers of pDCs in peripheral lymph nodes. Dotted lines in A: median plasma viral load of the 50 AID50 group (gray) and of the 5000 AID50 group (black).

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