Gene expression of PBMCs treated with rATG or hATG. Differential expression in PBMCs relative to mean expression level for 852 probe sets having greater than 2-fold change in response to 10 μg/mL rATG compared with control and less than a 10% false discovery rate. Red and blue indicate up- or down-regulation, respectively. Probe sets ordered according to a hierarchical clustering. (A) Gene expression patterns from treatment with rATG or hATG at 10 μg/mL. (B) Dose-response of rATG or hATG. Expression patterns were derived from 3 healthy donors and generated using Affymetrix HG-U133A 2.0 oligonucleotide GeneChips.