Representative EC gene expression patterns from CD40 signaling upon HUVEC/CD154⁺ T-cell interaction. Up-regulated (left flank) and down-regulated (right flank) genes, and their corresponding mean fold changes, at 4 hours (▭) and 16 hours (▬) after Jurkat D1.1 stimulation. Genes are arranged according to their related molecular and cellular functions. The underlined genes have been validated by RT-qPCR (see Figure 3 for details). Columns marked with an asterisk correspond to genes found significantly and differentially regulated between 4 and 16 hours by SAM analysis (FDR q-val = 0). Genes previously known to be induced by CD40 in ECs are highlighted in bold.