Representative gene sets induced upon CD40 signaling in ECs challenged by interaction with Jurkat D1.1 (CD154⁺) T cells. GSEA lists of selected induced gene sets (see “Microarray data analysis”) arranged according to their related molecular and cellular functions. Comparison of misRNA-2–treated versus siRNA-2–treated HUVEC transcriptional profiles at 4 hours and 16 hours after Jurkat D1.1 (CD154⁺) T-cell stimulation. A complementary list of CD40-dependent differentially regulated gene sets between 4 hours and 16 hours (4 h vs 16 h) is also given. For each functional gene set, its corresponding normalized enrichment score (NES) and FDR q-val is shown. Gene sets are ranked according to their FDR q-val. Positive NES values indicate up-regulated gene sets; negative NES values indicate down-regulated gene sets.