CMV-antigen high responders induce greater migration of PBMCs than CMV low responders. Results are shown as the mean transmigrated cell number per milliliter of 2 pooled sample sets. (A) Cell-migration results are shown from a 1:10 dilution of culture supernatants prepared from high- or low-responder donor CD4⁺ T-cell and endothelial cocultures. (B) Cell-migration results from a 1:100 dilution of culture supernatants from low and high responders. The highest levels of cell migration are seen with high-responder culture supernatants. For all samples, the background level of migration was subtracted. After subtracting background cell-migration values, results were then graphed as the mean (± SD).