VWF level does not correlate with the degree of Stx-induced thrombocytopenia. Plasma VWF levels were obtained for the Vwf+/+ and Vwf+/− mice shown in Figure 1, and were plotted against the percentage platelet decrease from baseline for each mouse. The R value was calculated using Microsoft Excel (Microsoft, Redmond, WA). Diamonds indicate Vwf+/+ mice; squares, Vwf+/− mice.