Figure 2
Figure 2. Administration of IL-7 or IL-15 during contraction rescues different CD8+ T-cell subsets. (A) Splenocytes were harvested on day 17 of the experiment outlined in Figure 1A, and expression of the indicated cell surface markers on donor cells was analyzed by flow cytometry. (B) CD127 and KLRG1 coexpression on antigen-specific donor and endogenous CD8+ T cells at days 17 and 15, respectively, as described in Figure 1A and D. (C) Absolute numbers of donor OT-I (left) or tetramer+ (right) CD8+ T-cell subsets as gated in panel B. All data are representative of 2 independent experiments.

Administration of IL-7 or IL-15 during contraction rescues different CD8+ T-cell subsets. (A) Splenocytes were harvested on day 17 of the experiment outlined in Figure 1A, and expression of the indicated cell surface markers on donor cells was analyzed by flow cytometry. (B) CD127 and KLRG1 coexpression on antigen-specific donor and endogenous CD8+ T cells at days 17 and 15, respectively, as described in Figure 1A and D. (C) Absolute numbers of donor OT-I (left) or tetramer+ (right) CD8+ T-cell subsets as gated in panel B. All data are representative of 2 independent experiments.

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